Read Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations (Springer Theses) by Iman Tavassoly Online

Read [Iman Tavassoly Book] * Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations (Springer Theses) Online * PDF eBook or Kindle ePUB free. Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations (Springer Theses) A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. To understand the function of this response in cancer cells, he has provided a systems biolog

Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations (Springer Theses)

Title : Dynamics of Cell Fate Decision Mediated by the Interplay of Autophagy and Apoptosis in Cancer Cells: Mathematical Modeling and Experimental Observations (Springer Theses)
Author :
Rating : 4.33 (628 Votes)
Asin : 3319365126
Format Type : paperback
Number of Pages : 79 Pages
Publish Date : 2013-06-17
Language : English

A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment. From the Back CoverThis interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. To understand the function of this response in cancer cells, he has provided a systems biology experimenta

very integrative resource on Autophagy and is a very useful introduction for cell death pathways in cancer and systems Sam It is a very integrative resource on Autophagy and is a very useful introduction for cell death pathways in cancer and systems biology of cancer.

He graduated from medical school in 2007 and received his PhD in Genetics, Bioinformatics and Computational Biology at Virginia Tech where he was awarded as the outstanding interdisciplinary program doctoral student. . Iman Tavassoly (MD, PhD) is a physician-scientist working at Icahn School of Medicine at Mount Sinai and Systems Biology Center New York. His research interests include systems biology of complex diseases and cancer biology

A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. In this dynamic model autophagy acts as a gradual response to stress (Rheostat) that delays the initiation of bistable switch of apoptosis to give the cells an opportunity to survive. To understand the function of this response in cancer cells, he has provided a systems biology experimental framework to study quantitative and dynamical aspects of autophagy in single cancer cells using live-cell imaging and quantitative fluorescence microscopy. This framework can provide new insights on function of autophagic response in cancer cells.. The author shows that his dynamical model is consistent with existing quantitative measurements of time courses of autophagic responses to cisplatin treatment

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