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* Read ^ The Implicit Genome by Oxford University Press ↠ eBook or Kindle ePUB. The Implicit Genome Beyond the Central Dogma This book is an exciting series of chapters which illustrate how far science has come from the discovery of the double helix structure and the triplet code which were thought to enable DNA to be read like a long string of text. Research discussed in the book indicates that there are levels of information encoded by genomes beyond the linear chain of bases, and hints that learning to interpret these additional levels of information will provide a wealth of insight]
| Title | : | The Implicit Genome |
| Author | : | |
| Rating | : | 4.31 (761 Votes) |
| Asin | : | 019517271X |
| Format Type | : | paperback |
| Number of Pages | : | 400 Pages |
| Publish Date | : | 2014-04-27 |
| Language | : | English |
Lynn Helena Caporale received her Ph.D. in Molecular Biology from the University of California at Berkeley and is the author of Darwin and the Genome. She is the Associate Director for Comparative Genomics at the Judith P. Dr. Sulzberger Genome Center at Columbia University.
While we have learned much based on this assumption, there is much we have missed. Even protein-coding regions can carry additional information, taking advantage of the flexible coding options provided by the degeneracy of the genetic code. In its beautiful simplicity, this structure, along with the table of codons worked out in the following decade, had entranced us into believing that we can fully understand the information content of a DNA sequence, simply by treating it as text that is read in a linear fashion. Some are "gene rich", some mobile, some full of repeats and duplications, some sticking together across long evolutionary distances, some readily breaking apart in tumor cells. The chapters in this volume touch on one or more of three interconnected themes; information can be implied, rather than explicit, in a genome; information can lea
Beyond the Central Dogma This book is an exciting series of chapters which illustrate how far science has come from the discovery of the double helix structure and the triplet code which were thought to enable DNA to be read like a long string of text. Research discussed in the book indicates that there are levels of information encoded by genomes beyond the linear chain of bases, and hints that learning to interpret these additional levels of information will provide a wealth of insight
Lynn Caporale has done a great service in highlighting some of the major challenges in contemporary genomics."--Dan Hartl, Higgins Professor of Biology, Harvard University, and Member National Academy of Sciences"This timely, critical evaluation ofundeciphered genomic information is of interest both for life scientists and for all those who are fascinated by the natural driving forces of life and its evolution."--Werner Arber, Emeritus Professor of Molecular Microbiology, University of Basel, Switzerland, and Nobel Laureate in Medicine"The book, thr
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